After the death of Nola, the Safari Park’s last northern white rhino, and with only three of these rhinos left on the planet, San Diego Zoo Global made a commitment to try to bring northern white rhinos back from the very brink of extinction. How? With “genetic rescue”: using artificial insemination techniques and eggs and sperm from the Frozen Zoo. In July 2017, Institute for Conservation Research scientists accomplished their first artificial insemination attempt on a southern white rhinoceros at the Rhino Rescue Center—a key step in the science-based, collaborative effort to develop and perfect the necessary assisted reproductive technologies. The procedure was not the first time artificial insemination had been used with a rhino, but it was a first for San Diego Zoo Global researchers. If this effort successfully produced a healthy rhino calf, the scientists would be on their way to determining the next steps.